Rheumatoid arthritis and hyaluronic acid.

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Studies of hyaluronic acid in rheumatoid arthritis.

It has previously been shown that in most joint diseases changes occur in the hyaluronic acid in the joint fluid. In diseased fluids the hyaluronic acid has a considerably lower degree of polymerization than in normal fluids or in uncomplicated traumatic effusions (Sundblad, 1953). The hyaluronic acid changes are especially marked in rheumatoid arthritis. We recently demonstrated (Sundblad, Ege...

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The Hyaluronic Acid of Synovial Fluid in Rheumatoid Arthritis.

Rheumatoid arthritis *is considered a disease which involves the connective tissue and supporting structures of the body with its primary nidus in the interfibrillar ground substance of these structures (1). The ground substances are thought to be composed of mucopolysaccharide-protein complexes. The nature of two of the polysaccharides is known-chondroitin sulfuric acid and hyaluronic acid. Th...

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Relationship between serum hyaluronic acid level and disease activity in early rheumatoid arthritis.

OBJECTIVES To measure hyaluronic acid (HA) levels, which are raised in active rheumatoid arthritis (RA), in patients with early RA, and to assess the correlation with clinical and laboratory indices of disease activity and with subsequent radiographic erosive status. PATIENTS AND METHODS Patients fulfilling ACR criteria were recruited into a prospective cohort within 6 months of disease onset...

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Background: Changes in patients’ bone mineral density (BMD) is one of the problems in patients with rheumatoid arthritis, which can be due to the use of corticosteroid drugs to reduce patients' symptoms or due to the aging process in patients. In this study, we decided to compare BMD in patients with psoriatic arthritis and rheumatoid arthritis. Methods: This study as a cross-sectional descrip...

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ژورنال

عنوان ژورنال: Ensho

سال: 1995

ISSN: 0389-4290,1884-4006

DOI: 10.2492/jsir1981.15.439